MiXCR processes big immunome data from raw sequences
to quantitated clonotypes. MiXCR is:

• Universal: effectively processes data from most of existing sample preparation protocols
  • Extracts both T- and B-cell receptor repertoires
  • Extracts repertoire data even from regular RNA-Seq
  • Successfully analyses full-length antibody data
• Sensitive: specially optimized alignment algorithms extract maximum from your datasets
• Robust: carefully assembles clonotypes correcting for false diversity, arising from PCR and sequencing errors
• Verbose: provides comprehensive information for assembled clonotypes and alignments
• Simple: requires zero parameters for a typical analysis*
• and yet very flexible
  • all analysis parameters are well-documented and
    can be customized
  • clones can be assembled using custom sequence parts
    (e.g. allows for full-length antibody clonotype assembly)
  • lots of intermediate information can be transparently
    extracted for custom analysis or evaluation of analysis / sample preparation issues

* for analysis of non-human data, species must be specified.

Please see documentation for details.

Cite MiXCR as:

Bolotin D et al. MiXCR: software for comprehensive adaptive immunity profiling. Nature methods 12, no. 5 (2015): 380-381. doi:10.1038/nmeth.3364

For commercial use please contact licensing@milaboratory.com.

Image from Bolotin et al., 2015, Nat methods, doi:10.1038/nmeth.3364